How to calculate the required number of bioreactors for batch and fed-batch fermentation.

You will need this information to work with:Yearly requirement of productFermentation yield Yf Down stream processing yield Yd/pFermentation timeCleaning and sterilization timeDown time (days when the plant shuts off)Failure rateWorking bioreactor volume Start by calculating the working days by subtracting the down time from 365 days.Calculate 1 cycle duration = cleaning and sterilization time + … Read more How to calculate the required number of bioreactors for batch and fed-batch fermentation.